HEAL Initiative: HEALthy Brain and Child Development (HBCD) Study
Application Deadline: Feb. 17, 2026
Grant Description: This opportunity will support large-scale, multi-site research to recruit and follow approximately 7,200 pregnant women and their children from the second trimester through childhood. The study will examine the effects of prenatal and perinatal exposures, such as opioids, marijuana, stimulants, alcohol, and nicotine, on brain and behavioral development to inform future interventions that promote child health and resilience.
Limited Competition for the HEAL Initiative: HEALthy Brain and Child Development (HBCD) Study – Coordinating Administrative Core and Data Coordinating Center
Application Deadline: Feb. 17, 2026
Grant Description: This opportunity will fund the Coordinating Administrative Core and Data Coordinating Center for the HBCD Study, which will oversee leadership, management, and consortium-wide activities while standardizing, integrating, and sharing data across research sites. The HBCD cohort includes ~7,200 mother-child dyads, and this renewal continues funding for the second 5-year period
Maternal and Pediatric Precision in Therapeutics (MPRINT) Knowledge and Research Coordination Center
Application Deadline: March 2, 2026
Grant Description: This opportunity will establish a Knowledge and Research Coordination Center as part of NICHD’s MPRINT Hub to advance safe, effective drug development for maternal and pediatric populations. The Center will develop a curated, interoperable pharmacology knowledgebase, leverage real-world clinical data, support innovative clinical trials, and unite multidisciplinary expertise to train the next generation of researchers. It will also collaborate with the Maternal Medication and Human Milk Research Center to conduct cutting-edge clinical, translational, and data science research.
Maternal Medications and Human Milk Research Center
Application Deadline: March 2, 2026
Grant Description: This opportunity will establish a Maternal Medication and Human Milk Research Center within NICHD’s MPRINT Hub to study how maternal medications affect human milk composition and infant health. The Center will identify knowledge gaps, integrate real-world and bioanalytic data, develop tools to improve medication safety and efficacy, and disseminate findings to clinicians, researchers, and families. It will collaborate with MPRINT’s Knowledge and Research Coordination Center (KRCC) to advance clinical, translational, and data science research.
Translational Research in Maternal and Pediatric Pharmacology and Therapeutics
Application Deadline: May 7, 2026
Grant Description: This opportunity supports translational and clinical research to improve safe and effective precision therapeutics for pregnant and lactating women, fetuses, neonates, and children, including those with disabilities. Funded through NOFO, projects will advance precision medicine by developing novel tools, models, and technologies with direct clinical impact; enhance understanding of drug action through studies on pediatric development and the physiological changes of pregnancy and lactation; and promote the discovery or repurposing of therapeutics to support safer, more effective treatment options for these populations.
Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities
Application Deadline: Nov. 15, 2027
Grant Description: This opportunity leverages NICHD clinical research network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. This NOFO will utilize a bi-phasic (UG3/UH3), milestone-driven mechanism consisting of a start-up phase (UG3) and a full enrollment and clinical study implementation phase (UH3).
Patient Centered Outcomes Research Institute - Call for Merit Reviewers
Application Deadline: Applications are accepted on a rolling basis
Grant Description: The Patient-Centered Outcomes Research Institute (PCORI) is seeking Merit Reviewers who share a commitment to patient-centered research and an interest in helping PCORI fulfill its mission of funding research that can help patients, clinicians, and other stakeholders make more informed health and healthcare decisions. Merit Review Panels consist of scientific, patient, and other stakeholder reviewers whose scores are equally weighted to ensure that all perspectives are heard.
Understanding the Impact of Healthcare System and Clinician Factors on Disparities in Maternal Morbidity and Mortality
FY 2025 (PAR-24-059) Estimated Application Deadline: Click on grant link to view full timeline.
Grant Description: Supports multidisciplinary and innovative intervention research to understand and address maternal mortality and maternal morbidity in the U.S., particularly among racial and ethnic minorities, socioeconomically disadvantaged and underserved rural populations.
Funding: HRSA anticipates approximately $11 million will be available to fund up to 15 awards.
Eligibility: Click on grant link to view full list.
